Transcutaneous vagus nerve stimulation reduces total striatal GABA+ content, increases DLPFC Glu content, and facilitates early-phase motor learning
tVNS (1) reduced striatal GABA+ levels and increased DLPFC Glu in healthy adults, and (2) facilitated early-phase motor learning. These findings support the use of tVNS as a noninvasive intervention that enhances motor learning in neurorehabilitation and the treatment of motor disorders.
Authors
- Tomoyuki Fumuro
- Hiroyuki Matsuta (ORCID: https://orcid.org/0000-0003-3659-1343)
- Nobuhiro Hata (ORCID: https://orcid.org/0000-0002-8132-0895)
- Yoshiki Asayama
- Ryushin Kawasoe
- Kojiro Matsushita
- Hisato Sugata
- Tsuyoshi Shimomura
- Kana Matsumura
Institutions
- Oita University (JP)
- Akita University (JP)
- Akita University of Nursing and Welfare (JP)
- Oita University Hospital (JP)
- Gifu University (JP)
- International University of Health and Welfare (JP)
- Oita University of Nursing and Health Sciences (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2026-02-18
- DOI
- https://doi.org/10.3389/fnhum.2026.1731345
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science