Comparative Outcomes of Drug-Eluting Stents Versus Drug-Eluting Balloons in Patients with Chronic Kidney Disease: A Systematic Review of Current Evidence

In CKD/ESRD patients, DEB and DES yield equivalent MACE, though TLR/TVF results vary by study design, CKD severity, and procedural factors. No clear superiority emerged, supporting individualized strategy selection based on lesion characteristics, bleeding risk, and expertise. Prospective RCTs with standardized CKD subgroups and DEB optimization are needed for definitive guidance.PROSPERO registration ID: CRD420251039001 (05/15/2025).