Phenotypic and genotypic characterization of antimicrobial-resistant uropathogens in community settings of India: A multicentric cross-sectional study
This study revealed a wider presence of drug-resistant high-risk clones of uropathogens in community settings of India. A multifaceted approach through routine antimicrobial resistance surveillance, judicious choice of empiric antibiotics in a community setting, is deemed necessary. Whole-genome sequencing analysis of extended-spectrum beta-lactamase-producing E. coli isolates revealed a predominance of ST131 lineage (25%), while ST1193 strains carried IncFIA and ColKP3 plasmids associated with bla<sub>CTX-M-15</sub> and bla<sub>TEM-1B</sub>. ST231 K. pneumoniae isolates harboured bla<sub>OXA-32</sub> gene along with ColKP3 plasmid.
Authors
- Dibyabhaba Pradhan (ORCID: https://orcid.org/0000-0002-2459-5032)
- Sneha Chunchanur (ORCID: https://orcid.org/0000-0002-7564-5773)
- Rajesh Kumari (ORCID: https://orcid.org/0000-0002-6219-9970)
- Susmita Chaudhuri
- Pankaj Hari
- Arti Kapil
- Vibhor Tak
- Seema Sood
- Sumit Malhotra
- Shashi Kant
- Rajashree Panigrahy
- Mani Kalaivani
- Bimal Kumar Das
- Manisha Yadav
- Harshal Ramesh Salve
- Swati Pundir
- Shwetha Venugopal
- Hitender Gautam
- Arvind Kumar
Institutions
- All India Institute of Medical Sciences Raipur (IN)
- All India Institute of Medical Sciences Jodhpur (IN)
- Translational Health Science and Technology Institute (IN)
- Central Road Research Institute (IN)
- All India Institute of Medical Sciences Bhopal (IN)
- Institute of Medical Sciences and Sum Hospital (IN)
- All India Institute of Medical Sciences (IN)
- Bangalore Medical College and Research Institute (IN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1016/j.jgar.2026.02.003
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00