Factors Associated With Oral Epithelial Dysplasia in Oral Potentially Malignant Disorders

Although PMD type was not globally associated with OED severity, leukoplakia was linked to low-grade OED, whereas leukoerythroplakia and PVL tended to show higher OED severity. Lesion heterogeneity and involvement of the floor of the mouth emerged as the most relevant clinical features related to moderate/severe OED, highlighting their relevance in the risk stratification of PMDs.