Extensive antibiotic use during early life and risk of frailty: a population-based cohort study in the UK biobank
Our findings indicate that extensive antibiotic use during early life is associated with elevated risk of frailty in middle and older adulthood. They highlight the importance of prudent antibiotic use in early life and the need for additional studies to explore the underlying causal pathways.
Authors
- Xueshan Sun
- Jiaqi Peng
- Xuemei Zhen
- Jiamin Wang (ORCID: https://orcid.org/0009-0008-1697-4578)
- Dongshan Zhu
- Qi Wang
- Bingsong Li
- Cecilia Stålsby Lundborg
Institutions
- Shandong University (CN)
- Karolinska Institutet (SE)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- BMC Public Health
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1186/s12889-026-26612-0
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00