Characterization of mesocolic adipose hyperplasia in a rat 2,4,6-trinitrobenzenesulfonic acid colitis model and comparison to creeping fat in Crohn disease
Mesocolic hyperplasia, closely replicating the key histopathological and molecular features of CD-related CrF, developed in half of the rats in this model. This model provides a cost-effective platform for studying the interplay between intestinal inflammation and mesenteric adipose tissue remodeling.
Authors
- Carolina Serena (ORCID: https://orcid.org/0000-0003-2251-0856)
- Ramón Bartolí (ORCID: https://orcid.org/0000-0002-0636-0942)
- Diandra Monfort-Ferré (ORCID: https://orcid.org/0000-0003-3832-4249)
- A Boronat-Toscano (ORCID: https://orcid.org/0000-0003-2650-156X)
- R Suau (ORCID: https://orcid.org/0000-0003-3754-4768)
- Laura Clua
- Míriam Mañosa
- Micaella Jaenna Aquino
- Karol Matute-Molina
- Lauro Sumoy
- Josep Manye
- Eugeni Domènech
- Montserrat Guasch
- Mireya Jimeno
Institutions
- Hospital de Viladecans (ES)
- Institut de Recerca Biomèdica Catalunya Sud (ES)
- Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (ES)
- Hospital Universitari Germans Trias i Pujol (ES)
- Medical Research Network (US)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1093/ibd/izaf328
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00