Performance of CEUS LI-RADS v2017 major feature combinations: individual patient data meta-analysis

CEUS LI-RADS demonstrated progressively higher PPVs from LR-3 to LR-5, supporting its ability to stratify risk across HCC categories. Major feature combinations performed similarly within each category, indicating internal consistency of the system. Although only PPVs were assessed, the results align with trends seen in CT/MRI LI-RADS, with wider confidence intervals in CEUS reflecting smaller sample sizes.

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Publication Details

Journal
Abdominal Radiology
Published
2026-02-18
DOI
https://doi.org/10.1007/s00261-026-05417-0
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Performance of CEUS LI-RADS v2017 major feature combinations: individual patient data meta-analysis

Adam Polikoff, Li‐Da Chen, Hyo Jin Kang, J. Eisenbrey et al.
Abdominal Radiology
Hepatocellular Carcinoma Treatment and Prognosis
article

Performance of CEUS LI-RADS v2017 major feature combinations: individual patient data meta-analysis

Adam Polikoff, Li‐Da Chen, Hyo Jin Kang, J. Eisenbrey, Robert G. Adamo, Deike Strobel, Mostafa Alabousi, Mohammed Kashif Al-Ghita, Bernardo Stefanini, Jean‐Paul Salameh, Barbara Meitner-Schellhaas, Wei Wang, Andreu Costa, Eleonora Terzi, Mustafa R. Bashir, Stephanie R. Wilson, Rawan Awad, Fabio Piscaglia, Haresh Naringrekar, Christian B. van der Pol, Xiang Jing, Eric Lam
article en

Abstract

CEUS LI-RADS demonstrated progressively higher PPVs from LR-3 to LR-5, supporting its ability to stratify risk across HCC categories. Major feature combinations performed similarly within each category, indicating internal consistency of the system. Although only PPVs were assessed, the results align with trends seen in CT/MRI LI-RADS, with wider confidence intervals in CEUS reflecting smaller sample sizes.

Abdominal Radiology
University of North Carolina at Chapel Hill (US), Thomas Jefferson University (US), University of Ottawa (CA), Sun Yat-sen University (CN), University of Calgary (CA), Queen Elizabeth II Health Sciences Centre (CA), Ottawa Hospital (CA), Juravinski Hospital (CA), Foothills Medical Centre (CA), Seoul National University Hospital (KR), Universitätsklinikum Erlangen (DE), Tianjin Third Central Hospital (CN), Azienda USL di Bologna (IT), Duke Medical Center (US), The First Affiliated Hospital, Sun Yat-sen University (CN), William Osler Health System (CA), Ottawa Hospital Research Institute (CA), Toronto Metropolitan University (CA), Tianjin Medical University (CN), University of Bologna (IT), McMaster University (CA)
Openalex Percentile: Top 52%
Hepatocellular Carcinoma Treatment and Prognosis
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