Acral Pseudolymphomatous Angiokeratoma of Childhood Successfully Treated With Topical Sirolimus

This report details the case of a 4-year-old girl diagnosed with acral pseudolymphomatous angiokeratoma of childhood (APACHE). Treatment with topical sirolimus 0.4% once daily led to almost complete resolution of the lesions. No adverse effects were observed after 1 year of follow-up.

Authors

Institutions

Publication Details

Journal
Pediatric Dermatology
Published
2026-02-18
DOI
https://doi.org/10.1111/pde.70175
Primary Topic
Cutaneous lymphoproliferative disorders research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Acral Pseudolymphomatous Angiokeratoma of Childhood Successfully Treated With Topical Sirolimus

José Javier Mateos Rico, Isabel Colmenero, Laura Victoria, A. Torrelo et al.
Pediatric Dermatology
Cutaneous lymphoproliferative disorders research
article

Acral Pseudolymphomatous Angiokeratoma of Childhood Successfully Treated With Topical Sirolimus

José Javier Mateos Rico, Isabel Colmenero, Laura Victoria, A. Torrelo, Pau Mora Capdevila
article en

Abstract

This report details the case of a 4-year-old girl diagnosed with acral pseudolymphomatous angiokeratoma of childhood (APACHE). Treatment with topical sirolimus 0.4% once daily led to almost complete resolution of the lesions. No adverse effects were observed after 1 year of follow-up.

Pediatric Dermatology
Hospital Universitario Quirónsalud Madrid (ES), Hospital Infantil Universitario Niño Jesús (ES), Hospital Universitario HM Madrid (ES)
Openalex Percentile: Top 50%
Cutaneous lymphoproliferative disorders research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.