Rethinking dynamics: static amino acid PET parameters vs. dynamic amino acid PET parameters for the detection of tumor progression in patients with post-treatment glioma

This study suggests that dynamic and static AA-PET parameters have similar diagnostic capacities to distinguish TP from TRA. While static AA-PET parameters may suffice for clinical decision-making, this study did not formally assess the incremental value of using dynamic metrics in addition to static measures.

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Publication Details

Journal
Frontiers in Nuclear Medicine
Published
2026-02-18
DOI
https://doi.org/10.3389/fnume.2026.1762984
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Rethinking dynamics: static amino acid PET parameters vs. dynamic amino acid PET parameters for the detection of tumor progression in patients with post-treatment glioma

Stephan Striepe, M Schürer, Dylan Jozef Hendrik Augustinus Henssen, Katja Jähne et al.
Frontiers in Nuclear Medicine
Glioma Diagnosis and Treatment
article

Rethinking dynamics: static amino acid PET parameters vs. dynamic amino acid PET parameters for the detection of tumor progression in patients with post-treatment glioma

Stephan Striepe, M Schürer, Dylan Jozef Hendrik Augustinus Henssen, Katja Jähne, Cordula Scherlach, Andreas Schildan, Swen Hesse, Osama Sabri, Ruth Stassart, Michael Rullmann
article en

Abstract

This study suggests that dynamic and static AA-PET parameters have similar diagnostic capacities to distinguish TP from TRA. While static AA-PET parameters may suffice for clinical decision-making, this study did not formally assess the incremental value of using dynamic metrics in addition to static measures.

Frontiers in Nuclear MedicineVol. 6
Radboud University Nijmegen (NL), University Medical Center (US), Radboud University Medical Center (NL), University Hospital Leipzig (DE), Leipzig University (DE)
Good health and well-being
Openalex Percentile: Top 52%
Glioma Diagnosis and Treatment
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Rethinking dynamics: static amino acid PET parameters vs. dynamic amino acid PET parameters for the detection of tumor progression in patients with post-treatment glioma — Stephan Striepe, M Schürer, et al. · Frontiers in Nuclear Medicine (2026) | TGRS Research Map | TGRS