Curcumin ameliorates aflatoxin B1-induced brain toxicity in ducks by attenuating inflammation and PANoptosis
AFB1 could trigger PANoptosis and activate the TLR4/NF-κB signaling pathway, leading to brain damage in ducks. Curcumin exerted a significant protective effect by inhibiting these pathways, suggesting its potential as a therapeutic agent for alleviating mycotoxin-induced neurological damage.
Authors
- Renbin Chen
- Hang Pan (ORCID: https://orcid.org/0000-0001-7628-6787)
- Zhiwen Wu (ORCID: https://orcid.org/0000-0002-2785-5581)
- Yanli You
- Lianmei Hu
- Xuanliang Li
- Xudong Han
- Yueyang Li
- Jianzhao Liao
- Limeng Zhou
- Ying He
Institutions
- South China Agricultural University (CN)
- Yantai University (CN)
- Guangxi Veterinary Research Institute (CN)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- Poultry Science
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1016/j.psj.2026.106652
- Primary Topic
- Mycotoxins in Agriculture and Food
- Type
- article
- Field-Weighted Citation Impact
- 0.00