A multi-machine learning framework identifies novel PANoptosis-related biomarkers and their immune landscape in ulcerative colitis: Insights from transcriptomics and experimental validation

This study effectively discovers six PANoptosis-related biomarkers with potential diagnostic value for UC, emphasizing their role in disease progression and immune regulation, offering new biomarkers for the early diagnosis and personalized treatment of UC.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-18
DOI
https://doi.org/10.3389/fimmu.2026.1729942
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

A multi-machine learning framework identifies novel PANoptosis-related biomarkers and their immune landscape in ulcerative colitis: Insights from transcriptomics and experimental validation

Ni Zhu, Hao Wang, Siliu Xu, Xiangjie Zhai et al.
Frontiers in Immunology
Inflammatory Bowel Disease
article

A multi-machine learning framework identifies novel PANoptosis-related biomarkers and their immune landscape in ulcerative colitis: Insights from transcriptomics and experimental validation

Ni Zhu, Hao Wang, Siliu Xu, Xiangjie Zhai, Sen Wang, Yuan Zhao
article en

Abstract

This study effectively discovers six PANoptosis-related biomarkers with potential diagnostic value for UC, emphasizing their role in disease progression and immune regulation, offering new biomarkers for the early diagnosis and personalized treatment of UC.

Frontiers in ImmunologyVol. 17
Integrated Optoelectronics (Norway) (NO), Hubei University of Science and Technology (CN)
Openalex Percentile: Top 49%
Inflammatory Bowel Disease
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