Peptide-based antimicrobial effect against carbapenem-resistant Acinetobacter baumannii: preclinical drug assessment and translational potential
Our findings indicate that DD-S052P in combination with colistin may represent a promising therapeutic option for CRAB infections. Further research is required to elucidate the mechanisms by which DD-S052P overcomes existing carbapenem resistance and validate its clinical applicability.
Authors
- Youngchang Kim (ORCID: https://orcid.org/0000-0002-1610-4889)
- Hak Jun Lee
- Seung Pyo Choi
- Yoon Hyun Sung
- Seung Min Park
- Seung Jun Lee
- Young Kyung Yoon
Institutions
- Korea University (KR)
- Konkuk University (KR)
- Department of Science and Technology (IN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-18
- DOI
- https://doi.org/10.3389/fphar.2026.1732644
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00