120 kVp Single‐Energy CT calibration for radiation treatment planning by cross‐calibration with Dual‐Energy CT using biological phantoms

The proposed methodology is novel in employing biological phantoms and consecutive, multi-energy CT acquisitions, ensuring both biological representativeness and practicality. Since multi-energy CT imaging can be performed on any conventional scanner, the approach is easily transferable across centers. It may serve not only for developing new clinical calibration curves but also as a robust tool for validating existing ones.