Statewide analysis of outcomes in patients with early-stage rectal cancer undergoing standard-of-care upfront resection

There is a considerable margin, nodal and EMVI upstaging rate in patients with early-stage rectal cancer undergoing standard care upfront TME, particularly those with low tumours. This highlights the limitations of current clinical staging in rectal cancer, leading to early-staged patients potentially being undertreated.

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Publication Details

Journal
European Journal of Surgical Oncology
Published
2026-02-19
DOI
https://doi.org/10.1016/j.ejso.2026.111484
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
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article

Statewide analysis of outcomes in patients with early-stage rectal cancer undergoing standard-of-care upfront resection

Elizabeth Murphy, Tiong Cheng Sia, Tracy R. Fitzsimmons, Darren Tonkin et al.
European Journal of Surgical Oncology
Colorectal Cancer Surgical Treatments
article

Statewide analysis of outcomes in patients with early-stage rectal cancer undergoing standard-of-care upfront resection

Elizabeth Murphy, Tiong Cheng Sia, Tracy R. Fitzsimmons, Darren Tonkin, Isuri Apsara Kumari Seneviratne, Ishraq Murshed, Sergei Bedrikovetski, Zachary Bunjo, Tarik Sammour
article en

Abstract

There is a considerable margin, nodal and EMVI upstaging rate in patients with early-stage rectal cancer undergoing standard care upfront TME, particularly those with low tumours. This highlights the limitations of current clinical staging in rectal cancer, leading to early-staged patients potentially being undertreated.

European Journal of Surgical OncologyVol. 52(4)
Royal Adelaide Hospital (AU), Lyell McEwin Hospital (AU), Flinders Medical Centre (AU), Queen Elizabeth Hospital (AU), The University of Adelaide (AU)
Openalex Percentile: Top 50%
Colorectal Cancer Surgical Treatments
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