The mediating role of activities of daily living in the association between intrinsic capacity and health-related quality of life: evidence from the WHO ICOPE pilot in China
Intrinsic capacity impairment is associated with compromised HRQoL both directly and indirectly by exacerbating functional dependence. Preserving functional independence serves as a key pathway connecting intrinsic capacity to well-being. These findings highlight the imperative for integrated interventions that simultaneously bolster intrinsic capacity and support daily functional ability, tailored to diverse living environments to promote healthy aging.
Authors
- Yan Dong (ORCID: https://orcid.org/0000-0003-3553-1488)
- Junzi Dong (ORCID: https://orcid.org/0000-0002-0382-1141)
- Linlin Hu
- Yiying Yang (ORCID: https://orcid.org/0000-0001-7755-7956)
- Yinxia Li
- Haijun Zhao
- Lulu Xiao
- Zhe Jin
- Ping Yang
- Zhen Wu
Institutions
- Xuzhou Medical College (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Chengdu Medical College (CN)
- Huawei Technologies (China) (CN)
- Peking Union Medical College Hospital (CN)
- Beijing Geriatric Hospital (CN)
- The First People’s Hospital of Lianyungang (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Aging Clinical and Experimental Research
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1007/s40520-026-03347-x
- Primary Topic
- Health disparities and outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00