Diagnostic Accuracy of Urine Microbial Diversity and Urine Neutrophil Gelatinase-Associated Lipocalin for the Diagnosis of Urinary Tract Infections in Children with Spina Bifida

NGAL is specific, and Shannon Diversity Index is sensitive, for diagnosing UTI in children with spina bifida who use clean intermittent catheterization. However, the combination of the 2 markers does not create improved predictive accuracy over either alone.

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Publication Details

Journal
The Journal of Pediatrics
Published
2026-02-18
DOI
https://doi.org/10.1016/j.jpeds.2026.115043
Primary Topic
Urinary Tract Infections Management
Type
article
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article

Diagnostic Accuracy of Urine Microbial Diversity and Urine Neutrophil Gelatinase-Associated Lipocalin for the Diagnosis of Urinary Tract Infections in Children with Spina Bifida

Kerry A. Tepe, Asumi Gibeau, Stephanie Davis, Nader Shaikh et al.
The Journal of Pediatrics
Urinary Tract Infections Management
article

Diagnostic Accuracy of Urine Microbial Diversity and Urine Neutrophil Gelatinase-Associated Lipocalin for the Diagnosis of Urinary Tract Infections in Children with Spina Bifida

Kerry A. Tepe, Asumi Gibeau, Stephanie Davis, Nader Shaikh, Calise Curry, Catherine S. Forster, Bhanu Sharma
article en

Abstract

NGAL is specific, and Shannon Diversity Index is sensitive, for diagnosing UTI in children with spina bifida who use clean intermittent catheterization. However, the combination of the 2 markers does not create improved predictive accuracy over either alone.

The Journal of PediatricsVol. 293
Cincinnati Children's Hospital Medical Center (US), University of Pittsburgh (US)
Industry, innovation and infrastructure, Responsible consumption and production
Openalex Percentile: Top 51%
Urinary Tract Infections Management
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