Protective Effects of Jiawei Baihu Tang in Kawasaki Disease: Omics Analysis and Mechanistic Exploration
For the first time, this study unveiled the multi-target mode of action of JWBHT in KD through the crosstalk between ECM and lipid metabolism, and LCN2 was identified as a potential novel intervention target. Our findings suggest that JWBHT is a promising traditional Chinese medicine for preventing the cardiovascular complications of KD.
Authors
- Jin Ma (ORCID: https://orcid.org/0000-0003-2919-5457)
- Y. Tang
- Haitao Lv
- Xuan Li
- Yexing Chen
- Peng Cao
- Xiudao Song
Institutions
- Nanjing University of Chinese Medicine (CN)
- Soochow University (CN)
- Suzhou Traditional Chinese Medicine Hospital (CN)
- Children's Hospital of Suzhou University (CN)
Publication Details
- Journal
- Cardiovascular Drugs and Therapy
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1007/s10557-026-07849-8
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00