Association of Plasma Biomarkers of Immunothrombosis With Death in Patients With Coronavirus Disease 2019 on Extracorporeal Membrane Oxygenation

We found increased immunothrombotic markers, male sex, and history of smoking were risk factors in patients with COVID-19 on ECMO who died as compared to those who were decannulated. These findings are important for understanding the pathogenesis of severe COVID-19 and prognostication.

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Publication Details

Journal
The Journal of Infectious Diseases
Published
2026-02-14
DOI
https://doi.org/10.1093/infdis/jiag106
Primary Topic
Mechanical Circulatory Support Devices
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Plasma Biomarkers of Immunothrombosis With Death in Patients With Coronavirus Disease 2019 on Extracorporeal Membrane Oxygenation

Emily Ricotta, Kapil Saharia, Nicole Hays, Peter Rock et al.
The Journal of Infectious Diseases
Mechanical Circulatory Support Devices
article

Association of Plasma Biomarkers of Immunothrombosis With Death in Patients With Coronavirus Disease 2019 on Extracorporeal Membrane Oxygenation

Emily Ricotta, Kapil Saharia, Nicole Hays, Peter Rock, Andrew P. Platt, Viviane Callier, Zonghui Hu, Raymond Rector, Marcos Javier Ramos-Benítez, Jocelyn Wu, Sydney Stein, Sabrina Ramelli, Seth Warner, Miranda Gibbons, Jeffrey R. Strich, Ronson J. Madathil, Ryan Curto, Sabrina Cho, Megan Anders, T. Stantliff, M. Vannella Kevin, Daniel S Chertow, Douglas Tran, Katherine Raja, Dean Follmann, Robert Christenson, James Dickey, Ali Tabatabai, Katelyn Wagner, Thomas Scalea, Joseph Rabin, Shreya Singireddy, Madeleine Purcell, Michael T McCurdy, Daniel Herr
article en

Abstract

We found increased immunothrombotic markers, male sex, and history of smoking were risk factors in patients with COVID-19 on ECMO who died as compared to those who were decannulated. These findings are important for understanding the pathogenesis of severe COVID-19 and prognostication.

The Journal of Infectious Diseases
University of Maryland, Baltimore (US), National Institutes of Health (US), University of Maryland Medical Center (US), Ponce Health Sciences University (PR), National Heart, Lung, and Blood Institute (US), Institute of Human Virology (NG), Frederick National Laboratory for Cancer Research (US), National Institute of Allergy and Infectious Diseases (US), National Cancer Institute (US), Center for Cancer Research (US), National Institutes of Health Clinical Center (US), St. Joseph Medical Center (US), WellSpan York Hospital (US)
Good health and well-being
Openalex Percentile: Top 53%
Mechanical Circulatory Support Devices
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