Hepatic Safety of Adjunctive High-Dose Melatonin in Participants Receiving Ocrelizumab for Primary Progressive Multiple Sclerosis: Liver Toxicity Findings from a Phase I/II Randomised Clinical Trial (MELATOMS-1)

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Publication Details

Journal
CNS Drugs
Published
2026-02-18
DOI
https://doi.org/10.1007/s40263-025-01261-w
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00

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article

Hepatic Safety of Adjunctive High-Dose Melatonin in Participants Receiving Ocrelizumab for Primary Progressive Multiple Sclerosis: Liver Toxicity Findings from a Phase I/II Randomised Clinical Trial (MELATOMS-1)

Maria Angeles Geniz, Juan Luis Ruíz-Peña, María Ángeles Lobo-Acosta, María Isabel García-Sánchez et al.
CNS Drugs
Circadian rhythm and melatonin
article

Hepatic Safety of Adjunctive High-Dose Melatonin in Participants Receiving Ocrelizumab for Primary Progressive Multiple Sclerosis: Liver Toxicity Findings from a Phase I/II Randomised Clinical Trial (MELATOMS-1)

Maria Angeles Geniz, Juan Luis Ruíz-Peña, María Ángeles Lobo-Acosta, María Isabel García-Sánchez, A. Carrillo-Vico, Eduardo Ponce España, Guillermo Ayuso Izquierdo, Ana Isabel Álvarez López, V Merino-Bohórquez, Rocío López-Ruiz, Javier Ampuero, Sara Eichau, Patricia Judith Lardone, Juan Miguel Guerrero, Manuel Cameán, Ignacio Bejarano, Silvia Jiménez-Jorge, Clara María Rosso-Fernández
article en

Abstract

No abstract available for this paper.
CNS DrugsVol. 40(4)
Hospital Universitario Virgen Macarena (ES), Biobanco del Sistema Sanitario Público de Andalucía (ES), Hospitales Nisa (ES), Instituto de Biomedicina de Sevilla (ES), Hospital Universitario Virgen del Rocío (ES), Universidad de Sevilla (ES)
Universidad de Sevilla, European Regional Development Fund
Good health and well-being
Openalex Percentile: Top 49%
Circadian rhythm and melatonin
DOIOpen Access PDFOpenAlex
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Hepatic Safety of Adjunctive High-Dose Melatonin in Participants Receiving Ocrelizumab for Primary Progressive Multiple Sclerosis: Liver Toxicity Findings from a Phase I/II Randomised Clinical Trial (MELATOMS-1) — Maria Angeles Geniz, Juan Luis Ruíz-Peña, et al. · CNS Drugs (2026) | TGRS Research Map | TGRS