Cocirculation of endemic and recently introduced West Nile Virus lineage 1 clades in Southern Spain
In 2024, Andalusia (Southern Spain) reported its largest recent West Nile virus (WNV) outbreak, with 106 confirmed human cases and 16 deaths. Genomic analysis of 27 WNV isolates revealed the co-circulation of multiple WNV lineage 1 clades, including both endemic and recently introduced strains, reflecting a marked increase in viral genetic diversity. These findings underscore the critical role of integrated genomic surveillance systems in monitoring pathogen evolution and supporting timely public health responses to emerging zoonotic threats.
Authors
- María Navarro-Marí José
- Cristina Gómez-Camarasa
- Irene Pedrosa-Corral (ORCID: https://orcid.org/0000-0002-1565-8513)
- Sara Sanbonmatsu‐Gámez (ORCID: https://orcid.org/0000-0003-1859-927X)
- Carlos S. Casimiro‐Soriguer (ORCID: https://orcid.org/0000-0003-1774-2580)
- Dopazo Joaquín
- Javier Perez-Florido
- Maria Lara
- J. Alberto Chaves
- Jose A. Lepe
- Nicola Lorusso
- Laura Merino
Institutions
- Instituto de Salud Carlos III (ES)
- Fundación Progreso y Salud (ES)
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital Universitario Virgen de las Nieves (ES)
- Instituto de Biomedicina de Sevilla (ES)
- Consejería de Salud y Consumo (ES)
- Hospital Universitario Virgen del Rocío (ES)
Publication Details
- Journal
- One Health
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1016/j.onehlt.2026.101368
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Horizon 2020 Framework Programme
- Instituto de Salud Carlos III
- European Regional Development Fund