Development and validation of a cut-off chart for predicting postoperative liver dysfunction following PFNA fixation: composite endpoint and Boruta-based analysis

A novel nomogram for predicting PLD in ITF patients after PFNA was successfully developed and internally validated. Using easily accessible clinical variables, this tool enables accurate early risk stratification, helping clinicians identify high-risk patients and optimize peri-operative care. It highlights the importance of inflammatory, coagulation, and fracture-related factors in PLD prediction for this cohort.

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Publication Details

Journal
European journal of medical research
Published
2026-02-18
DOI
https://doi.org/10.1186/s40001-026-04048-x
Primary Topic
Hip and Femur Fractures
Type
article
Field-Weighted Citation Impact
0.00
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article

Development and validation of a cut-off chart for predicting postoperative liver dysfunction following PFNA fixation: composite endpoint and Boruta-based analysis

Zhu Zhu, Le Hu, Linbing Lou, Jihang Dai et al.
European journal of medical research
Hip and Femur Fractures
article

Development and validation of a cut-off chart for predicting postoperative liver dysfunction following PFNA fixation: composite endpoint and Boruta-based analysis

Zhu Zhu, Le Hu, Linbing Lou, Jihang Dai, Luqi Yuan
article en

Abstract

A novel nomogram for predicting PLD in ITF patients after PFNA was successfully developed and internally validated. Using easily accessible clinical variables, this tool enables accurate early risk stratification, helping clinicians identify high-risk patients and optimize peri-operative care. It highlights the importance of inflammatory, coagulation, and fracture-related factors in PLD prediction for this cohort.

European journal of medical researchVol. 31(1)
Dalian Medical University (CN), Northern Jiangsu People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 52%
Hip and Femur Fractures
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Development and validation of a cut-off chart for predicting postoperative liver dysfunction following PFNA fixation: composite endpoint and Boruta-based analysis — Zhu Zhu, Le Hu, et al. · European journal of medical research (2026) | TGRS Research Map | TGRS