Hepatic arterial infusion chemotherapy (HAlC) versus sorafenib for hepatocellular carcinoma (HCC) in Barcelona Clinic Liver Cancer (BCLC) B/C: A systematic review and meta-analysis
In Asian and African patients with BCLC stage B/C hepatocellular carcinoma, HAIC-particularly the FOLFOX regimen-confers superior overall survival and oncologic outcomes compared to sorafenib, with higher response and disease control rates and reduced disease progression.
Authors
- Yaotian Fan
- Yuting Luo
- Zhengqiang Chen
- Xiwen Ye
- Zhen You
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1371/journal.pone.0342495
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00