Association Between Ferritinophagy and M1 Macrophage Polarization During the Acute Phase of Childhood Allergic Asthma

Our research results indicate that macrophages in the acute phase model of allergic asthma in young mice exhibit M1 polarization, and an increase in ferritinophagy is associated with the pathogenesis of allergic asthma. These findings establish an associative (not causal) relationship between the two processes, providing new ideas for therapeutic strategies.

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Publication Details

Journal
Journal of Inflammation Research
Published
2026-02-01
DOI
https://doi.org/10.2147/jir.s569956
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between Ferritinophagy and M1 Macrophage Polarization During the Acute Phase of Childhood Allergic Asthma

Ren Shen, Xiaofeng Shi, Yelin Jiang, Jingjing Li et al.
Journal of Inflammation Research
Immune cells in cancer
article

Association Between Ferritinophagy and M1 Macrophage Polarization During the Acute Phase of Childhood Allergic Asthma

Ren Shen, Xiaofeng Shi, Yelin Jiang, Jingjing Li, Xing Wang
article en

Abstract

Our research results indicate that macrophages in the acute phase model of allergic asthma in young mice exhibit M1 polarization, and an increase in ferritinophagy is associated with the pathogenesis of allergic asthma. These findings establish an associative (not causal) relationship between the two processes, providing new ideas for therapeutic strategies.

Journal of Inflammation ResearchVol. Volume 19
Hangzhou Hospital of Traditional Chinese Medicine (CN), First Hospital of Jiaxing (CN), Dazhou Central Hospital (CN), Yuxian People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 50%
Immune cells in cancer
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