Immunogenicity and Safety of Two-dose Schedules With Different Intervals of an ORF7-deficient Live Vaccine Candidate for Varicella: A Randomized, Double-blind, Controlled, Phase 2b Trial
The 2-dose regimens of v7D vaccine demonstrated robust immune responses and excellent safety profiles. These findings warrant further evaluation of the safety advantages and efficacy v7D vaccine in the future.
Authors
- J. Jillian Zhang (ORCID: https://orcid.org/0009-0007-7613-6966)
- Qi Liang (ORCID: https://orcid.org/0000-0001-6175-8366)
- Shoujie Huang
- Xiafei Chu
- X D Liu
- Mengjun Liao
- Xiangzhong Ye
- M. L. ZHANG
- Jin‐Bo Xu
- Hua Zhu
- H Pan
- Yaru Quan
- Changgui Li
- Lingxian Qiu
- Yingying Su
- T Cheng
- Jiaxue Li
- Jinle Han
- Ningshao Xia
- Ting Wu
- Jialei Hu
- Jizong Jia
- Lu Chen
- Wei Wang
- Sheng Liu
- Zhen Chen
Institutions
- Rutgers, The State University of New Jersey (US)
- Xiamen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- National Institutes for Food and Drug Control (CN)
- Beijing Wantai Biological Pharmacy (China) (CN)
- Gansu Provincial Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1097/inf.0000000000005184
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00