Beyond origin: multimodal AI synthesis to resolve cancers of unknown primary
For decades, the central dogma of oncology has been that a cancer’s identity is inextricably linked to its anatomical origin. This principle underpins the entire diagnostic and therapeutic framework, from histology-based classification to site-specific treatment guidelines. Yet, this framework
Authors
- Hongru Shen (ORCID: https://orcid.org/0000-0001-9147-6044)
- Xiangchun Li
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
Publication Details
- Journal
- Cancer Biology and Medicine
- Published
- 2026-02-16
- DOI
- https://doi.org/10.20892/j.issn.2095-3941.2025.0636
- Primary Topic
- Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Tianjin City