A preliminary investigation of gene expression and levels of FSH, IL-10, and TNF-α and histological staining in natural aging mice
Aging BALB/c mice exhibit disrupted estrous cycles, ovarian fibrosis, increased FSH and TNF-α, and reduced IL-10, changes that resemble those associated with menopause. These findings support the use of aging BALB/c mice as a model for reproductive aging and therapeutic studies.
Authors
- Abdurahman Laqif (ORCID: https://orcid.org/0000-0002-6642-5701)
- Soetrisno Soetrisno
- Yulice Soraya Nur Intan
Institutions
- Sebelas Maret University (ID)
- Sultan Agung Islamic University (ID)
Publication Details
- Journal
- Journal of Turkish Society of Obstetric and Gynecology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.4274/tjod.galenos.2026.94515
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00