<i>Lactobacillus delbrueckii</i> : A Functional Powerhouse in Dairy Fermentation and Emerging Probiotic Applications

<i>Lactobacillus delbrueckii</i> is a key lactic acid bacterium (LAB) widely used in dairy fermentation, particularly in the production of yogurt, cheese, and kefir. Its metabolic activities-such as efficient lactose utilization, rapid acidification, and high proteolytic activity-make it an indispensable starter culture in the dairy industry. Beyond its technological advantages, <i>L. delbrueckii</i> contributes significantly to human health through the production of bioactive peptides (BAPs), extracellular polysaccharides (EPS), and other functional metabolites with antioxidant, anti-inflammatory, and immunomodulatory effects. Recent studies have also highlighted its role in gut health, cholesterol reduction, and potential anti-cancer activity, underscoring its value as a probiotic. This review provides a comprehensive overview of the taxonomy, metabolism, and health-promoting properties of <i>L. delbrueckii</i> while also exploring its potential applications in precision fermentation and the development of functional foods. The insights discussed herein position <i>L. delbrueckii</i> as a promising candidate for next-generation probiotic dairy innovations.

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Publication Details

Journal
Food Science & Nutrition
Published
2026-02-01
DOI
https://doi.org/10.1002/fsn3.71546
Primary Topic
Probiotics and Fermented Foods
Type
article
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article

Lactobacillus delbrueckii : A Functional Powerhouse in Dairy Fermentation and Emerging Probiotic Applications

Anahita Barghi, Babak Haghshenas, Yousef Nami, Tara Farhadi et al.
Food Science & Nutrition
Probiotics and Fermented Foods
article

Lactobacillus delbrueckii : A Functional Powerhouse in Dairy Fermentation and Emerging Probiotic Applications

Anahita Barghi, Babak Haghshenas, Yousef Nami, Tara Farhadi, Mahsa Sadeghi
article en

Abstract

<i>Lactobacillus delbrueckii</i> is a key lactic acid bacterium (LAB) widely used in dairy fermentation, particularly in the production of yogurt, cheese, and kefir. Its metabolic activities-such as efficient lactose utilization, rapid acidification, and high proteolytic activity-make it an indispensable starter culture in the dairy industry. Beyond its technological advantages, <i>L. delbrueckii</i> contributes significantly to human health through the production of bioactive peptides (BAPs), extracellular polysaccharides (EPS), and other functional metabolites with antioxidant, anti-inflammatory, and immunomodulatory effects. Recent studies have also highlighted its role in gut health, cholesterol reduction, and potential anti-cancer activity, underscoring its value as a probiotic. This review provides a comprehensive overview of the taxonomy, metabolism, and health-promoting properties of <i>L. delbrueckii</i> while also exploring its potential applications in precision fermentation and the development of functional foods. The insights discussed herein position <i>L. delbrueckii</i> as a promising candidate for next-generation probiotic dairy innovations.

Food Science & NutritionVol. 14(2)
Kermanshah University of Medical Sciences (IR), Agricultural Biotechnology Research Institute of Iran (IR), Dong-A University (KR)
Industry, innovation and infrastructure
Openalex Percentile: Top 51%
Probiotics and Fermented Foods
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