<i>Lactobacillus delbrueckii</i> : A Functional Powerhouse in Dairy Fermentation and Emerging Probiotic Applications
<i>Lactobacillus delbrueckii</i> is a key lactic acid bacterium (LAB) widely used in dairy fermentation, particularly in the production of yogurt, cheese, and kefir. Its metabolic activities-such as efficient lactose utilization, rapid acidification, and high proteolytic activity-make it an indispensable starter culture in the dairy industry. Beyond its technological advantages, <i>L. delbrueckii</i> contributes significantly to human health through the production of bioactive peptides (BAPs), extracellular polysaccharides (EPS), and other functional metabolites with antioxidant, anti-inflammatory, and immunomodulatory effects. Recent studies have also highlighted its role in gut health, cholesterol reduction, and potential anti-cancer activity, underscoring its value as a probiotic. This review provides a comprehensive overview of the taxonomy, metabolism, and health-promoting properties of <i>L. delbrueckii</i> while also exploring its potential applications in precision fermentation and the development of functional foods. The insights discussed herein position <i>L. delbrueckii</i> as a promising candidate for next-generation probiotic dairy innovations.
Authors
- Anahita Barghi (ORCID: https://orcid.org/0009-0006-6666-133X)
- Babak Haghshenas (ORCID: https://orcid.org/0000-0001-9535-9128)
- Yousef Nami (ORCID: https://orcid.org/0000-0003-3726-2920)
- Tara Farhadi
- Mahsa Sadeghi
Institutions
- Kermanshah University of Medical Sciences (IR)
- Agricultural Biotechnology Research Institute of Iran (IR)
- Dong-A University (KR)
Publication Details
- Journal
- Food Science & Nutrition
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/fsn3.71546
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00