Clinical value of artificial intelligence in reducing PET image acquisition time: routine clinical validation using qualitative, quantitative, and radiomic analysis on a cohort of 282 patients undergoing [18F]FDG and [68Ga]Ga-PSMA-11 PET/CT

SubtlePET® improves the image quality of PET acquisitions performed with reduced acquisition times using [<sup>18</sup>F]FDG and [<sup>68</sup>Ga]Ga-PSMA. However, clinician confidence remains limited and, while denoised acquisitions preserve most radiomic features, others are altered, potentially limiting model transposability.

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Publication Details

Journal
EJNMMI Physics
Published
2026-02-18
DOI
https://doi.org/10.1186/s40658-026-00835-x
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
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article

Clinical value of artificial intelligence in reducing PET image acquisition time: routine clinical validation using qualitative, quantitative, and radiomic analysis on a cohort of 282 patients undergoing [18F]FDG and [68Ga]Ga-PSMA-11 PET/CT

M. Lacombe, F. Lacoeuille, C. Guillerminet, A. Dambrain et al.
EJNMMI Physics
Radiomics and Machine Learning in Medical Imaging
article

Clinical value of artificial intelligence in reducing PET image acquisition time: routine clinical validation using qualitative, quantitative, and radiomic analysis on a cohort of 282 patients undergoing [18F]FDG and [68Ga]Ga-PSMA-11 PET/CT

M. Lacombe, F. Lacoeuille, C. Guillerminet, A. Dambrain, C. Bouron, O. Morel, P. A. Dufour, A. Testard, S. Girault
article en

Abstract

SubtlePET® improves the image quality of PET acquisitions performed with reduced acquisition times using [<sup>18</sup>F]FDG and [<sup>68</sup>Ga]Ga-PSMA. However, clinician confidence remains limited and, while denoised acquisitions preserve most radiomic features, others are altered, potentially limiting model transposability.

EJNMMI PhysicsVol. 13(1)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers (FR), Institut de Cancérologie de l'Ouest (FR), Université d'Angers (FR)
Openalex Percentile: Top 52%
Radiomics and Machine Learning in Medical Imaging
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