Plasma GFAP and NLRP3 Associate with Cognitive Impairment After Recent Small Subcortical Infarct via Periventricular White Matter Hyperintensity

Elevated plasma GFAP and NLRP3 are associated with post-stroke cognitive impairment in RSSI, partially mediated by PWMH. These biomarkers may help identify patients at risk of early cognitive decline.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2026-02-01
DOI
https://doi.org/10.1002/cns.70780
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Plasma GFAP and NLRP3 Associate with Cognitive Impairment After Recent Small Subcortical Infarct via Periventricular White Matter Hyperintensity

Tian Yang, Rong Lei, Yuying Yan, Chunhua Wang et al.
CNS Neuroscience & Therapeutics
Cerebrovascular and Carotid Artery Diseases
article

Plasma GFAP and NLRP3 Associate with Cognitive Impairment After Recent Small Subcortical Infarct via Periventricular White Matter Hyperintensity

Tian Yang, Rong Lei, Yuying Yan, Chunhua Wang, Bo Wu, Rongfeng Luo, Jingyu Cui, Shuai Jiang, Tianxiang Lan
article en

Abstract

Elevated plasma GFAP and NLRP3 are associated with post-stroke cognitive impairment in RSSI, partially mediated by PWMH. These biomarkers may help identify patients at risk of early cognitive decline.

CNS Neuroscience & TherapeuticsVol. 32(2)
Sichuan University (CN), West China Hospital of Sichuan University (CN), Sichuan Cancer Hospital (CN)
National Natural Science Foundation of China, Sichuan University, National Science and Technology Major Project, West China Hospital, Sichuan University
Openalex Percentile: Top 51%
Cerebrovascular and Carotid Artery Diseases
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