Time-dependent coagulation declines in cold-stored whole blood: a paired in-vitro comparison of rotational thromboelastometry and SEER sonorheometry
Our experimental in vitro study of stored WB exhibits steady, time-dependent hemostatic deterioration, particularly in platelet function and clot initiation. These in-vitro observations reveal early declines in platelet-driven clot stiffness in our model and are hypothesis-generating for further laboratory and clinical evaluation.
Authors
- Patricio Castillo
- Susan Watts
- Jesse Qiao (ORCID: https://orcid.org/0000-0002-8348-4893)
- Edward A. Michelson (ORCID: https://orcid.org/0000-0003-4468-8962)
- Bradford Ray
- Diluma Kariyawasam
- Leann Rodriguez
Institutions
- Texas Tech University (US)
- University of California, Irvine (US)
- University Medical Center of El Paso (US)
- University of California, Irvine Medical Center (US)
- Texas Tech University Health Sciences Center (US)
Publication Details
- Journal
- Blood Coagulation & Fibrinolysis
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1097/mbc.0000000000001418
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00