The progressive journey of poor-responder neovascular AMD: tracking structural evolution and visual decline over time
Poor-responder neovascular AMD follows a three-phase evolutionary journey with subretinal fibrosis as the dominant independent predictor of visual decline. These findings demand a paradigmatic shift toward qualitative structural assessment focusing on fibrotic changes rather than thickness-based monitoring.
Authors
- Giacomo Boscia (ORCID: https://orcid.org/0000-0002-8768-899X)
- Pasquale Viggiano (ORCID: https://orcid.org/0000-0002-0323-967X)
- Ilaria Lolli (ORCID: https://orcid.org/0000-0003-0023-0781)
- Maria Grazia Pignataro
- Giacomo Boscia
- Giovanni Alessio
- Alba Chiara Termite
- Enrico Borelli
- Giulia Ribezzi
- Michele Reibaldi
Institutions
- University of Turin (IT)
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Eye
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1038/s41433-026-04306-6
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00