Comparative Effectiveness of Vonoprazan Dosing Strategies in Bismuth-Based Quadruple Therapy for Helicobacter pylori Eradication: A Prospective Non-inferiority Cohort Study
Vonoprazan 20 mg once daily showed comparable efficacy to twice-daily dosing as part of a bismuth-based quadruple regimen for H. pylori eradication, with better cost-effectiveness, making it a promising option, especially in resource-limited settings.
Authors
- Shanjing Xu
- Lina Fang
- Xianbin Zhou
- Lingling Yan
- Jiali Ma
- Rong Lin
- Yu Xiang Zhang
Institutions
- Wenzhou Medical University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Zhejiang Center for Disease Control and Prevention (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- Zhejiang Taizhou Hospital (CN)
- Zhejiang Medicine (China) (CN)
Publication Details
- Journal
- The Turkish Journal of Gastroenterology
- Published
- 2026-02-13
- DOI
- https://doi.org/10.5152/tjg.2026.25645
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Science and Technology Project of Zhejiang Province
- Science and Technology Program of Zhejiang Province