Hepatic arterial infusion chemotherapy combined with apatinib plus camrelizumab for advanced hepatocellular carcinoma with type Vp4 portal vein tumor thrombosis: a multicenter propensity score-matching analysis

For HCC with Vp4 type PVTT, the combination regimen of HAIC plus apatinib and camrelizumab demonstrates promising efficacy in reducing both intrahepatic tumor burden and thrombus progression, representing a potentially viable treatment approach with an acceptable safety profile.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-17
DOI
https://doi.org/10.3389/fimmu.2026.1742116
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Hepatic arterial infusion chemotherapy combined with apatinib plus camrelizumab for advanced hepatocellular carcinoma with type Vp4 portal vein tumor thrombosis: a multicenter propensity score-matching analysis

Fengtao Zhang, M. Li, H. Zhang, Qian Cheng et al.
Frontiers in Immunology
Hepatocellular Carcinoma Treatment and Prognosis
article

Hepatic arterial infusion chemotherapy combined with apatinib plus camrelizumab for advanced hepatocellular carcinoma with type Vp4 portal vein tumor thrombosis: a multicenter propensity score-matching analysis

Fengtao Zhang, M. Li, H. Zhang, Qian Cheng, Dejun Xiong, Q. Wei, Sheng Zhong, Ankang Shu, Pingkang Chen, Xiang Zheng, Shaoteng Wu, Feifeng Qiu
article en

Abstract

For HCC with Vp4 type PVTT, the combination regimen of HAIC plus apatinib and camrelizumab demonstrates promising efficacy in reducing both intrahepatic tumor burden and thrombus progression, representing a potentially viable treatment approach with an acceptable safety profile.

Frontiers in ImmunologyVol. 17
Guangzhou University of Chinese Medicine (CN), Tung Wah Hospital (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), Shenzhen Sixth People's Hospital (CN), Zhuhai People's Hospital (CN), Chinese University of Hong Kong, Shenzhen (CN), First Affiliated Hospital of Guangdong Pharmaceutical University (CN), First Affiliated Hospital of Jinan University (CN), Anshan Hospital (CN), Guangzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 52%
Hepatocellular Carcinoma Treatment and Prognosis
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Hepatic arterial infusion chemotherapy combined with apatinib plus camrelizumab for advanced hepatocellular carcinoma with type Vp4 portal vein tumor thrombosis: a multicenter propensity score-matching analysis — Fengtao Zhang, M. Li, et al. · Frontiers in Immunology (2026) | TGRS Research Map | TGRS