EpiSmokEr2: a robust epigenetic classifier for smoking status inference using Illumina EPIC methylation data
EpiSmokEr2 provides a reliable DNAm-based estimator of smoking status. It is available as an open-source R package on GitHub, facilitating broad use in epidemiological and clinical research.
Authors
- Kaitlyn G. Lawrence (ORCID: https://orcid.org/0000-0002-8360-9326)
- Mikaela Hukkanen (ORCID: https://orcid.org/0000-0002-8574-8274)
- Aino Heikkinen (ORCID: https://orcid.org/0000-0001-5770-6475)
- Tianyu Zhu (ORCID: https://orcid.org/0000-0002-4781-7398)
- Jordana T. Bell (ORCID: https://orcid.org/0000-0002-3858-5986)
- Sailalitha Bollepalli (ORCID: https://orcid.org/0000-0002-8773-7149)
- Kristina Gervin (ORCID: https://orcid.org/0000-0002-9851-1890)
- Fang Fang (ORCID: https://orcid.org/0000-0003-1656-8285)
- Ricardo Costeira
- Teodora Farago
- Jaakko Kaprio
- Mari Roberts Spildrejorde
- Miina Ollikainen
- Olli Raitakari
- Yanyu Pan
- Dale P. Sandler
- Terho Lehtimäki
Institutions
- Oslo University Hospital (NO)
- National Institutes of Health (US)
- University of Helsinki (FI)
- University of Turku (FI)
- Tampere University (FI)
- RTI International (US)
- King's College London (GB)
- Turku University Hospital (FI)
- Minerva Foundation (FI)
- Diakonhjemmet Hospital (NO)
- DMH Associates (United States) (US)
Publication Details
- Journal
- Epigenomics
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1080/17501911.2026.2630841
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- Foundation for Cardiovascular Research
- Yrjö Jahnssonin Säätiö
- Wellcome Trust
- National Institute for Health and Care Research
- King's College London
- European Commission
- Suomen Kulttuurirahasto
- Jane ja Aatos Erkon Säätiö
- Juho Vainion Säätiö
- Signe ja Ane Gyllenbergin Säätiö
- Emil Aaltosen Säätiö
- Norges Forskningsråd
- Sydäntutkimussäätiö
- Tampereen Tuberkuloosisäätiö
- Diabetesliitto
- Paavo Nurmen Säätiö
- Tays
- Syöpäsäätiö
- Versus Arthritis
- National Institutes of Health
- Medical Research Council
- Engineering and Physical Sciences Research Council
- Biotechnology and Biological Sciences Research Council
- Economic and Social Research Council