Clinical and biological features of complicated and asymptomatic malaria among PLHIV and HIV-negative adults: An observational study in Libreville, Gabon

Compared to HIV negative, asymptomatic malaria was less frequent while severe malaria predominantly affects PLHIV with advanced immunosuppression, highlighting the importance of early detection and management of co-infection to reduce morbidity. Further studies are needed to investigate the neurological manifestations and the impact of prophylactic strategies in Libreville.

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Publication Details

Journal
PLoS ONE
Published
2026-02-17
DOI
https://doi.org/10.1371/journal.pone.0327068
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical and biological features of complicated and asymptomatic malaria among PLHIV and HIV-negative adults: An observational study in Libreville, Gabon

Héléna Noéline Kono, Charleine Manomba Boulingui, Bédrich Pongui Ngondza, Coella Joyce Mihindou et al.
PLoS ONE
Malaria Research and Control
article

Clinical and biological features of complicated and asymptomatic malaria among PLHIV and HIV-negative adults: An observational study in Libreville, Gabon

Héléna Noéline Kono, Charleine Manomba Boulingui, Bédrich Pongui Ngondza, Coella Joyce Mihindou, M. E. M. M. Owono, Ornella Anaïse Mbang Nguema, Christian Mayandza, Jacques Mari Ndong Ngomo, Marielle Karine Bouyou Akotet, Magalie Essomeyo Mebale, Ardin Dimitri Mabicka Moussavou, Noé Patrick Mbondoukwé, Bridy Chesly Moutombi Ditombi
article en

Abstract

Compared to HIV negative, asymptomatic malaria was less frequent while severe malaria predominantly affects PLHIV with advanced immunosuppression, highlighting the importance of early detection and management of co-infection to reduce morbidity. Further studies are needed to investigate the neurological manifestations and the impact of prophylactic strategies in Libreville.

PLoS ONEVol. 21(2)
Libreville Hospital (GA), Université des Sciences de la Santé (GA)
Good health and well-being
Openalex Percentile: Top 55%
Malaria Research and Control
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Clinical and biological features of complicated and asymptomatic malaria among PLHIV and HIV-negative adults: An observational study in Libreville, Gabon — Héléna Noéline Kono, Charleine Manomba Boulingui, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS