Metabolic Reprogramming and <scp>GM</scp> ‐ <scp>CSF</scp> Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression
ANE promotes epithelial-to-mesenchymal transition and GM-CSF secretion in fibroblasts, which activate EGFR signaling and malignant transformation of oral precancerous cells.
Authors
- S. Lo
- Pang‐Yu Chen (ORCID: https://orcid.org/0000-0002-5400-2832)
- Yuk‐Kwan Chen
- Leong‐Perng Chan (ORCID: https://orcid.org/0000-0001-8192-2725)
- Chih‐Huang Tseng (ORCID: https://orcid.org/0000-0001-8693-9200)
- Shih Sheng Jiang (ORCID: https://orcid.org/0000-0003-1909-437X)
- Shyng‐Shiou F. Yuan (ORCID: https://orcid.org/0000-0002-4753-788X)
- Yen‐Yun Wang
- Hieu D. H. Nguyen
- Chang‐Wei Su
Institutions
- Kaohsiung Medical University (TW)
- National Health Research Institutes (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
- Canniesburn Hospital (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- Oral Diseases
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1111/odi.70236
- Primary Topic
- Oral Health Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Education, India
- Kaohsiung Medical University
- Kaohsiung Medical University Chung-Ho Memorial Hospital
- National Science and Technology Council