18ï ¢-Glycyrrhetinic acid suppresses glioblastoma by regulating p38 signaling pathway: an integrative approach combining network analysis, transcriptomics, and experimental assessment
This study demonstrats that GA exerted potent anti-GBM effects by regulating p38 signaling pathway, provides novel mechanistic insights, and positions its as a promising therapeutic candidate against GBM.
Authors
- Cuiyan Ma (ORCID: https://orcid.org/0000-0002-1474-9034)
- Huilin Liu (ORCID: https://orcid.org/0000-0002-7974-6125)
- Yalei Wang (ORCID: https://orcid.org/0000-0002-7678-349X)
- Xue Wang (ORCID: https://orcid.org/0009-0005-9165-4150)
- Yuan Zeng
- Tiantian Peng
- Qian Hua
- Mujin Li
Institutions
- Beijing University of Chinese Medicine (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fphar.2026.1727072
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China