α <sub>5</sub> -GABA <sub>A</sub> allosteric modulation triggers and prolongs dopamine neuronal activity via AMPA receptors

L-655,708 enhanced VTA DA neuron population activity for up to 1 week after a single injection. This effect was dependent on AMPA and took place through action on the benzodiazepine site.

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Publication Details

Journal
Journal of Psychopharmacology
Published
2026-02-17
DOI
https://doi.org/10.1177/02698811251405691
Primary Topic
Neuroscience and Neuropharmacology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

α 5 -GABA A allosteric modulation triggers and prolongs dopamine neuronal activity via AMPA receptors

Mostafa El Mansari, Areebah Ahmed, Pierre Blier
Journal of Psychopharmacology
Neuroscience and Neuropharmacology Research
article

α 5 -GABA A allosteric modulation triggers and prolongs dopamine neuronal activity via AMPA receptors

Mostafa El Mansari, Areebah Ahmed, Pierre Blier
article en

Abstract

L-655,708 enhanced VTA DA neuron population activity for up to 1 week after a single injection. This effect was dependent on AMPA and took place through action on the benzodiazepine site.

Journal of Psychopharmacology
University of Ottawa (CA)
Openalex Percentile: Top 53%
Neuroscience and Neuropharmacology Research
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α <sub>5</sub> -GABA <sub>A</sub> allosteric modulation triggers and prolongs dopamine neuronal activity via AMPA receptors — Mostafa El Mansari, Areebah Ahmed, et al. · Journal of Psychopharmacology (2026) | TGRS Research Map | TGRS