Survival after pathological complete response following neoadjuvant chemotherapy <i>versus</i> chemoradiotherapy for oesophageal squamous cell carcinoma

Among patients who achieved pCR, postoperative outcomes varied considerably by neoadjuvant treatment modality. The markedly favourable prognosis associated with pCR after NAC suggests that these patients may represent an optimal candidate cohort for future evaluation of surgery-avoidance and watch-and-wait strategies.

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Publication Details

Journal
British journal of surgery
Published
2026-02-16
DOI
https://doi.org/10.1093/bjs/znag012
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Survival after pathological complete response following neoadjuvant chemotherapy versus chemoradiotherapy for oesophageal squamous cell carcinoma

T Aparicio, Jun Okui, Koji Kato, K. Nagashima et al.
British journal of surgery
Esophageal Cancer Research and Treatment
article

Survival after pathological complete response following neoadjuvant chemotherapy versus chemoradiotherapy for oesophageal squamous cell carcinoma

T Aparicio, Jun Okui, Koji Kato, K. Nagashima, T. Tsushima, Marie Nilsson, Shaoyuan Zhang, Y Sato, Satoru Matsuda, Guillaume Piessen, Thomas Ruhstaller, Yuko Kitagawa, Bianca Mostert, Peter Thuss-Patience, Hirofumi Kawakubo, Charlène van der Zijden, Fredrik Klevebro, Bas P L Wijnhoven, Lijie Tan, Hiroya Takeuchi
article en

Abstract

Among patients who achieved pCR, postoperative outcomes varied considerably by neoadjuvant treatment modality. The markedly favourable prognosis associated with pCR after NAC suggests that these patients may represent an optimal candidate cohort for future evaluation of surgery-avoidance and watch-and-wait strategies.

British journal of surgeryVol. 113(3)
Karolinska University Hospital (SE), Inserm (FR), Sun Yat-sen University (CN), University of Basel (CH), Keio University (JP), Université Paris Cité (FR), Université de Lille (FR), Fudan University (CN), Karolinska Institutet (SE), Hamamatsu University School of Medicine (JP), Shizuoka Cancer Center (JP), National Cancer Center (US), Keio University Hospital (JP), Zhongshan Hospital (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Hôpital Saint-Louis (FR), Swiss Group For Clinical Cancer Research (CH), Erasmus MC Cancer Institute (NL), CANTHER - Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers (FR), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 52%
Esophageal Cancer Research and Treatment
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