Eosinophilic inflammation in hereditary angioedema: a single-center real-world retrospective chart review study
Patients with HAE show biochemical evidence of increased eosinophil activation, suggesting a previously unrecognized inflammatory component beyond bradykinin-driven edema formation. Further studies should clarify clinical implications and the potential contribution to comorbidities and phenotypic variability.
Authors
- Andreas Recke (ORCID: https://orcid.org/0000-0002-7674-1804)
- Katharina Boch (ORCID: https://orcid.org/0000-0003-1899-4886)
- Dagmar von Bubnoff
- Ralf J Ludwig
Institutions
- LMU Klinikum (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fimmu.2026.1754405
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft