Amplifying radiation-induced anti-tumor immunity: the dual role of brachytherapy and low-dose total body irradiation
Our research indicates that brachytherapy offers superior immune modulation over external radiotherapy. When combined with low-dose total body irradiation, it transiently activates the systemic immune response.
Authors
- Chen Xie (ORCID: https://orcid.org/0000-0003-4753-1151)
- Jianjun Wang (ORCID: https://orcid.org/0000-0001-7039-7136)
- Yang Yang (ORCID: https://orcid.org/0000-0001-9887-0685)
- Zhouxue Wu
- Shaozhi Fu (ORCID: https://orcid.org/0000-0002-8666-4304)
- Yunxue Zheng
- Yingqi Gu
- Jian Gao
- Jingbo Wu
- Xiaoyin Zhang
- XinYi Wang
- Yue Chen
- Min Wu
Institutions
- Affiliated Hospital of Southwest Medical University (CN)
- Jilin Province Tumor Hospital (CN)
- Tibet Autonomous Region People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fimmu.2026.1771593
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- BT Group
- Southwest Medical University