FSTL1 promotes dendritic cell pyroptosis and immunosuppression in sepsis by inhibiting STING autophagy
Our findings demonstrate that FSTL1 correlates with impaired STING autophagic degradation and DC pyroptosis, suggesting a potential pathway contributing to septic immune dysfunction.
Authors
- Xingui Dai (ORCID: https://orcid.org/0009-0004-7109-761X)
- Lijun Guo (ORCID: https://orcid.org/0009-0004-0227-415X)
- Jinru Li
- Hua Ling
- Wentao Duan
- Qiong Li
- Jingyi Li
Institutions
- Xuzhou Medical College (CN)
- Chenzhou First People's Hospital (CN)
- Xiangnan University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1371/journal.pone.0340204
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00