HOTAIR promotes the progression of B-cell acute lymphoblastic leukemia by regulating the miR-326/IGF-1R axis and activating the PI3K/AKT signaling pathway
HOTAIR promotes the progression of B-ALL via the miR-326/IGF-1R axis and PI3K/AKT activation, suggesting its potential as a therapeutic target.
Authors
- Shishan Xiao
- Xinyu Zhao (ORCID: https://orcid.org/0000-0002-5128-4424)
- Minmin Jiang (ORCID: https://orcid.org/0000-0001-8369-1414)
- Hongqian Zhu
- Zhe Li (ORCID: https://orcid.org/0000-0002-7954-7396)
- Ya-Qin Jiang
- Xin Wen
- Qian-Qian Huang
- Si-Rui-Yun Ding
- Fang-Fang Xiong
- Sheng-Wen Huang
Institutions
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Hematology
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1080/16078454.2026.2627664
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00