A Switch in Iron Delivery Is Critical for Postnatal Kidney Development

TfR1 is the critical iron species targeting postnatal tubulogenesis, but in the embryo, TfR1 must be complemented by alternative iron species called NTBI. Iron deficient kidney disease is reversible postnatally.

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Publication Details

Journal
Kidney360
Published
2026-02-17
DOI
https://doi.org/10.34067/kid.0000001064
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

A Switch in Iron Delivery Is Critical for Postnatal Kidney Development

Christian Hinze, Abraham Levitman, Beatriz Desanti de Oliveira, Jacob Stauber et al.
Kidney360
Iron Metabolism and Disorders
article

A Switch in Iron Delivery Is Critical for Postnatal Kidney Development

Christian Hinze, Abraham Levitman, Beatriz Desanti de Oliveira, Jacob Stauber, Christian Rosenberger, Andrew Yaeh, Yue Yu, L Dionne, Neal Paragas, Rosemary V. Sampogna, Andrew Beenken, Kaitlyn Corbin, Efrat Bruck, Mélanie Viltard, Max Werth, Moe R. Mahjoub, Atlas Khan, Kai Martin Schmidt-Ott, Tian Shen, Aryan S. Ghotra, Andong Qiu, Kristen McNierney, Roger W. Boles, Jonathan Barasch, Rong Deng, Katherine Xu
article en

Abstract

TfR1 is the critical iron species targeting postnatal tubulogenesis, but in the embryo, TfR1 must be complemented by alternative iron species called NTBI. Iron deficient kidney disease is reversible postnatally.

Kidney360
Tongji University (CN), Albert Einstein College of Medicine (US), Montefiore Medical Center (US), University of Washington (US), University of Erfurt (DE), Washington University in St. Louis (US), Medizinische Hochschule Hannover (DE), Southwestern Medical Center (US), New York University (US), Columbia University (US), The University of Texas Southwestern Medical Center (US)
Zero hunger
Openalex Percentile: Top 51%
Iron Metabolism and Disorders
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