Resolving cognitive heterogeneity in white matter hyperintensities through integrated analyses of microbiome, metabolome, and brain glymphatic function

These findings provide preliminary insights into plausible microbiota-metabolites-glymphatic function-cognition associations in WMH, potentially informing more targeted interventions for vascular cognitive impairment.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2026-02-01
DOI
https://doi.org/10.1002/alz.71201
Citations
2
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
46.41

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article

Resolving cognitive heterogeneity in white matter hyperintensities through integrated analyses of microbiome, metabolome, and brain glymphatic function

X. Ronald Zhu, Xia Zhou, Yongqiang Yu, Mengwei Zhang et al.
2 citations
Alzheimer s & Dementia
Cerebrospinal fluid and hydrocephalus
46.41
article

Resolving cognitive heterogeneity in white matter hyperintensities through integrated analyses of microbiome, metabolome, and brain glymphatic function

X. Ronald Zhu, Xia Zhou, Yongqiang Yu, Mengwei Zhang, Xiaotao Xu, Jingjing Fang, Jiajia Zhu, Zhiqing Yan
article en
2 citations

Abstract

These findings provide preliminary insights into plausible microbiota-metabolites-glymphatic function-cognition associations in WMH, potentially informing more targeted interventions for vascular cognitive impairment.

Alzheimer s & DementiaVol. 22(2)
Anhui Medical University (CN), First Affiliated Hospital of Anhui Medical University (CN), China Construction Bank (CN)
National Natural Science Foundation of China, Anhui Medical University, Natural Science Foundation of Anhui Province
Openalex Percentile: Top 0%
Cerebrospinal fluid and hydrocephalus
46.41
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