Closed incision negative pressure wound therapy after emergency laparotomy: a systematic review and Meta-analysis of randomized controlled trials

In adult patients undergoing emergency laparotomy with primary abdominal closure, ciNPWT significantly reduces key incision-related complications, particularly superficial SSI and wound dehiscence. Its clinical benefit appears confined to incision-level outcomes, with no effect on systemic or multifactorial postoperative endpoints. These findings support the selective use of ciNPWT in high-risk emergency laparotomy patients and highlight the need for standardized application protocols and longer-term outcome assessment.

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Publication Details

Journal
World Journal of Emergency Surgery
Published
2026-02-17
DOI
https://doi.org/10.1186/s13017-026-00679-x
Primary Topic
Abdominal Surgery and Complications
Type
article
Field-Weighted Citation Impact
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article

Closed incision negative pressure wound therapy after emergency laparotomy: a systematic review and Meta-analysis of randomized controlled trials

Abd-Elfattah Kalmoush, Omar H. Salloum, Jamal Ahmad, Mahmoud Diaa Hindawi et al.
World Journal of Emergency Surgery
Abdominal Surgery and Complications
article

Closed incision negative pressure wound therapy after emergency laparotomy: a systematic review and Meta-analysis of randomized controlled trials

Abd-Elfattah Kalmoush, Omar H. Salloum, Jamal Ahmad, Mahmoud Diaa Hindawi, Nada S. Jibril, Mohammad Marrawani, Edward C. T. H. Tan, Ahmed Hamdy, Hamdi Elbelkasi, Mariam Elewidi, Andrew W. Kirkpatrick, Alaa R. AL-Ihribat
article en

Abstract

In adult patients undergoing emergency laparotomy with primary abdominal closure, ciNPWT significantly reduces key incision-related complications, particularly superficial SSI and wound dehiscence. Its clinical benefit appears confined to incision-level outcomes, with no effect on systemic or multifactorial postoperative endpoints. These findings support the selective use of ciNPWT in high-risk emergency laparotomy patients and highlight the need for standardized application protocols and longer-term outcome assessment.

World Journal of Emergency SurgeryVol. 21(1)
Radboud University Nijmegen (NL), Al-Azhar University (EG), Zagazig University (EG), Tanta University (EG), Massachusetts Academy of Math and Science at WPI (US), Foothills Medical Centre (CA), Radboud University Medical Center (NL), Palestine Polytechnic University (PS), Menoufia University (EG)
Good health and well-being
Openalex Percentile: Top 52%
Abdominal Surgery and Complications
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