Clinical improvement of protein-losing enteropathy after SGLT2 inhibitor therapy in an adult with failing Fontan circulation: a case report
This case highlights the potential benefit of SGLT-2i in managing Fontan failure complicated by PLE. Multicenter studies are needed to further investigate the efficacy, safety, and mechanism of action of SGLT-2i in this unique patient population.
Authors
- Emanuela Concetta D’Angelo (ORCID: https://orcid.org/0000-0002-6257-5913)
- Rosalinda Palmieri
- Veronica Bordonaro (ORCID: https://orcid.org/0000-0002-9011-0793)
- Claudia Montanaro (ORCID: https://orcid.org/0000-0001-8613-8139)
- Micol Rebonato
Institutions
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Lung Institute (US)
- Bambino Gesù Children's Hospital (IT)
- Imperial College London (GB)
Publication Details
- Journal
- European Heart Journal - Case Reports
- Published
- 2026-02-16
- DOI
- https://doi.org/10.1093/ehjcr/ytag117
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ospedale Pediatrico Bambino Gesù
- Ministero della Salute