Silver nanoparticles at sub-cytotoxic levels increase enteric pathogen invasion by compromising intestinal epithelial barrier integrity
Given the increasing use of AgNPs into orally ingested consumer products, these results underscore a potential health risk associated with chronic AgNPs ingestion and highlights the need to re-evaluate their safety in the context of gastrointestinal health and host-pathogen interactions.
Authors
- Sangeeta Khare (ORCID: https://orcid.org/0000-0002-9496-6636)
- Radwa A. Hanafy (ORCID: https://orcid.org/0000-0002-2712-9942)
- K. Gokulan
Institutions
- National Center for Toxicological Research (US)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.3389/fcimb.2026.1745955
- Citations
- 1
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 16.08
Funders
- U.S. Department of Energy
- U.S. Food and Drug Administration
- Oak Ridge Institute for Science and Education