CT-guided cyanoacrylate injection for spinal cerebrospinal fluid leaks in spontaneous intracranial hypotension: outcomes from an expanded cohort
These findings support CT-guided percutaneous cyanoacrylate as a versatile, effective, and safe therapy across SIH leak types, with high rates of favorable clinical outcomes and concordant brain imaging improvement. Future studies with standardized post-treatment spine imaging are needed to enable assessment of an anatomic closure endpoint, validate efficacy by leak type, and define this technique's role relative to other therapies.
Authors
- Ulysse Puel (ORCID: https://orcid.org/0000-0003-2773-3514)
- Oana Harsan (ORCID: https://orcid.org/0000-0003-3152-6024)
- Liang Liao
- Fábio Pires Botta
- Ahmed Balaazi
- Serge Bracard
- François Zhu
- Marc BRAUN
- Wassim ABOU LOUKOUL
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Centre de Recherche en Sciences et Technologies de l'Information et de la Communication (FR)
- Imagerie Adaptative Diagnostique et Interventionnelle (FR)
- Laboratoire Lorrain de Recherche en Informatique et ses Applications (FR)
- Université de Lorraine (FR)
Publication Details
- Journal
- Journal of Neuroradiology
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1016/j.neurad.2026.101544
- Primary Topic
- Neurosurgical Procedures and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00