Modulation of the intestinal microbiome and reversal of the immunosuppressive microenvironment by nanoparticles for chemoimmunotherapy in prostate cancer
CBZ/FA-CA-OCD NPs improve PCa chemoimmunotherapy by regulating gut microbiota, reversing immunosuppression, and enhancing T-cell infiltration. This nanomedicine-based strategy provides a promising approach to boost PCa treatment outcomes.
Authors
- Saipeng Chen (ORCID: https://orcid.org/0000-0002-8840-1153)
- Ruimin Hu
- Dinglin Zhang (ORCID: https://orcid.org/0009-0002-2934-4213)
- Youxin Liu
- Jun Zheng
- Jie Xu
- Yuhao Lei
- Jing Yang
- Wenhao Shen
- Qian Ju
- Zhicheng Liu
Institutions
- Army Medical University (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jare.2026.02.027
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00